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what is black seed powder good for

Inflamm.Res 2007;56(8):345-351. Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension. 9-14-2005;100(3):295-298. View abstract. Effect of black cumin (Nigella sativa) on cadmium-induced oxidative stress in the blood of rats. Saudi Pharmaceutical Journal (Saudi Arabia). Sarac G, Kapicioglu Y, Sener S, et al. People have used the seed to make medicine for over 2000 years. Boskabady, M. H., Mohsenpoor, N., and Takaloo, L. Antiasthmatic effect of Nigella sativa in airways of asthmatic patients. Raza M and et al. View abstract. 2004;40:111-116. El Obeid, A., Al Harbi, S., Al Jomah, N., and Hassib, A. Herbal melanin modulates tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) production. View abstract. View abstract. View abstract. 2001;39(5):391. Gali-Muhtasib, H., Kuester, D., Mawrin, C., Bajbouj, K., Diestel, A., Ocker, M., Habold, C., Foltzer-Jourdainne, C., Schoenfeld, P., Peters, B., Diab-Assaf, M., Pommrich, U., Itani, W., Lippert, H., Roessner, A., and Schneider-Stock, R. Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells. Ajenuz, Aranuel, Baraka, Black Caraway, Black Cumin, Black Cumin Seed Oil, Charnuska, Cheveux de Vénus, Cominho Negro, Comino Negro, Cumin Noir, Cyah Dane, Fennel Flower, Fitch, Graine de Nigelle, Graine Noire, Habatul Sauda, Habbatul Baraka, Kalajaji, Kalajira, Kalonji, Ketsah, La Grainer Noire, Love in a Mist, Mugrela, Nielle, Nigella sativa, Nigelle de Crête, Nigelle Cultivée, Nutmeg Flower, Poivrette, Roman-Coriander, Schwarzkummel, Seed of Blessing, Siyah Dane, Shoniz, Small Fennel, Toute Épice, Upakuncika. View abstract. Fixed oil of Black seed and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Res Vet.Sci 2010;88(3):400-404. Cell Biochem.Funct. 2007;21(5):559-566. Mahmoud, M. R., El Abhar, H. S., and Saleh, S. The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice. View abstract. 2. Build up of fat in the liver in people who drink little or no alcohol (nonalcoholic fatty liver disease or NAFLD). View abstract. View abstract. Kocyigit, Y., Atamer, Y., and Uysal, E. The effect of dietary supplementation of Nigella sativa L. on serum lipid profile in rats. Nagi, M. N. and Mansour, M. A. Traditionally, Black Cumin Seed Oil has been used for its stimulating, warming, and tonic properties as well as for its harmonizing effect on the mood. Coban, S., Yildiz, F., Terzi, A., Al, B., Aksoy, N., Bitiren, M., and Celik, H. The effects of Nigella sativa on bile duct ligation induced-liver injury in rats. View abstract. 2020;21(4):318-325. Phytother.Res. Arzneimittelforschung. View abstract. Hansen, J. T., Benghuzzi, H., Tucci, M., and Cason, Z. Antimicrob.Agents Chemother. J Ethnopharmacol. View abstract. Yildiz, F., Coban, S., Terzi, A., Savas, M., Bitiren, M., Celik, H., and Aksoy, N. Protective effects of Nigella sativa against ischemia-reperfusion injury of kidneys. Black seed powder mixed in honey: actually tastes great Black seed also helps as an analgesic, is good for weight loss, is anti-inflammatory and has many other great properties including stimulating the liver, helping elasticity of blood vessels, and stimulating tumor cell death while inhibiting kidney cell death. View abstract. 2010;25(2-3):307-314. J Infect.Chemother. essential oils and their major constituents, thymoquinone and beta-elemene. Proximate analysis and fatty acid composition of Nigella sativa (Kalonji) seed oil growing in Pakistan. J Ethnopharmacol 2015;175:147-52. el Dakhakhny, M., Mady, N. I., and Halim, M. A. Nigella sativa L. oil protects against induced hepatotoxicity and improves serum lipid profile in rats. View abstract. J Pak Med Assoc 1991;41:185-7. View abstract. Al Mofleh, I. View abstract. How do you use black seed oil? Black seed oil has been used in the treatment of a variety of skin conditions. J Nutrigenet.Nutrigenomics. Journal of Applied Sciences 2007;7(24):3909-3917. Inhibitory effect of Nigella sativa on histamine receptors of isolated guinea pig tracheal chains. Pharmaceutical Biology (Netherlands). 2004;93(1):19-23. J Toxicol.Sci 1978;3(1):51-56. Khalife, K. H. and Lupidi, G. Reduction of hypervalent states of myoglobin and hemoglobin to their ferrous forms by thymoquinone: the role of GSH, NADH and NADPH. View abstract. Effect of black cumin (Nigella sativa) on heart rate, some hematological values, and pancreatic beta-cell damage in cadmium-treated rats. J Ethnopharmacol 1996;52:23-6. View abstract. View abstract. Pak.J Biol.Sci 12-1-2007;10(23):4319-4322. Black seed oil, Nigella sativa, is ranked very highly among the world of herbal plants. View abstract. View abstract. Planta Med 1995;61:33-6. View abstract. J Ethnopharmacol. Seed Extracts Against Clinical Isolates from Skin Wound Infections. Indian J Physiol Pharmacol. Anat.Rec.A Discov.Mol.Cell Evol.Biol. He T, Xu X. Mansour, M. A. Abbas, A. T., Abdel-Aziz, M. M., Zalata, K. R., and Tel, Abd Al-Galel. The doctor will inform you about the possible drug interactions. View abstract. Asgari S and et al. View abstract. Epub 2019 Jan 22. Ahmad Alobaidi AH. Fixed oil of Black seed and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. View abstract. A pilot study on the effects of Nigella sativa seeds aqueous extract on paediatric intractable seizures. View abstract. Planta Med 2010;76(3):218-222. Al Majed, A. Early research shows that using a nasal spray containing black seed oil can reduce dryness, blockage, and crusting of the nostrils in elderly patients with nasal irritation. Al Homidan, A., Al Qarawi, A. Gali-Muhtasib, H. U., Abou Kheir, W. G., Kheir, L. A., Darwiche, N., and Crooks, P. A. Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes. But applying black seed oil ointment to the skin does not seem to help. View abstract. Hepatitis C. Early research shows that taking black seed oil daily for 3 months reduces viral load in people with hepatitis C. It also seems to reduce lower limb swelling. Nahrung 2002;46(4):240-244. El Obeid, A., Al Harbi, S., Al Jomah, N., and Hassib, A. Herbal melanin modulates tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) production. 1999;54(4):285-294. 2020;34(6):1367-1376. Nephrol.Dial.Transplant. New Chapter/Fermented Black Seed Booster Powder ($18.91/ounce) New Chapter also offers a Fermented Black Seed Booster Powder, specially designed for mental acuity and mood. View abstract. Salem, M. L. and Hossain, M. S. Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection. Corder, C., Benghuzzi, H., Tucci, M., and Cason, Z. Isik H, Cevikbas A, Gürer US, et al. specific immunotherapy in allergic rhinitis patients. Food Chem.Toxicol. Effect of Nigella sativa seed administration on prevention of febrile neutropenia during chemotherapy among children with brain tumors. Phytother.Res 2008;22(10):1311-1323. 2003;17(8):921-924. Phytother.Res. View abstract. Effects of thymoquinone, the major constituent of Nigella sativa seeds, on the contractile responses of rat vas deferens. Evid.Based Complement Alternat.Med 12-29-2009; View abstract. A skin disorder that causes white patches to develop on the skin (vitiligo). Med Sci Monit. View abstract. 1-30-2009;121(3):419-424. Saudi J Kidney Dis Transpl. Biomed.Sci Instrum. View abstract. Tennekoon KH, Jeevathayaparan S, Kurukulasooriya AP, Karunanayake EH. Diabetes Res 1991;18(4):163-168. J Pharm.Biomed.Anal. 9-7-2008;14(33):5204-5209. View abstract. View abstract. View abstract. Ragheb, A., Attia, A., Elbarbry, F., Prasad, K., and Shoker, A. Attenuated Combined Action of Cyclosporine A and Hyperlipidemia on Atherogenesis in Rabbits by Thymoquinone. Khader, M., Bresgen, N., and Eckl, P. M. Antimutagenic effects of ethanolic extracts from selected Palestinian medicinal plants. Basic Clin Pharmacol.Toxicol. J Ethnopharmacol. Erdurmus, M., Yagci, R., Yilmaz, B., Hepsen, I. F., Turkmen, C., Aydin, B., and Karadag, R. Inhibitory effects of topical thymoquinone on corneal neovascularization. Biomed.Sci Instrum. 2008;103(2):109-118. Mohtashami R, Huseini HF, Heydari M, et al. It is a good idea to find a naturalist doctor and to follow the treatment under his recommendations. Mohamed, A. M., Metwally, N. M., and Mahmoud, S. S. Sativa seeds against Schistosoma mansoni different stages. View abstract. View abstract. View abstract. Nutr Cancer 1991;16(1):67-72. Damage to the immune system caused by cancer drug treatment. Effect of Nigella sativa (kalonji) on serum cholesterol of albino rats. Parvardeh S and et al. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. El Mezayen, R., El Gazzar, M., Nicolls, M. R., Marecki, J. C., Dreskin, S. C., and Nomiyama, H. Effect of thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation. Kocyigit, Y., Atamer, Y., and Uysal, E. The effect of dietary supplementation of Nigella sativa L. on serum lipid profile in rats. 2007;21(9):895-897. Salim, E. I. and Fukushima, S. Chemopreventive potential of volatile oil from black cumin (Nigella sativa L.) seeds against rat colon carcinogenesis. A grouping of symptoms that increase the risk of diabetes, heart disease, and stroke (metabolic syndrome). View abstract. Acne. Mem.Inst.Oswaldo Cruz 2005;100(2):205-211. Saudi Pharmaceutical Journal (Saudi Arabia). View abstract. Saudi J Kidney Dis.Transpl. 2-18-2010; View abstract. Safety evaluation of Phytovagex, a pessary formulation of Nigella sativa, on pregnant rats. View abstract. Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats. Glycoconj.J 2007;24(8):497-507. Galus, R., Zandecki, L., Sajjad, E., Jozwiak, J., and Wlodarski, K. [Factors affecting melanogenesis and methods used for identification of pigmentation disorders]. Awad, E. M. and Binder, B. R. In vitro induction of endothelial cell fibrinolytic alterations by Nigella sativa. 2009;45:42-47. Abdel-Fattah, A. M., Matsumoto, K., and Watanabe, H. Antinociceptive effects of Nigella sativa oil and its major component, thymoquinone, in mice. Yar, T., El Hariri, M., El Bahai, M. N., and Bamosa, A. O. Res Vet.Sci 2005;79(3):219-223. View abstract. Iranian Journal of Pharmaceutical Research. Braz.J Med Biol.Res 2007;40(6):839-847. 2000;49(1):63-74. Hawsawi, Z. Asthma. A. and Gad el-Rab, M. O. Allergic contact dermatitis: clinical features and profile of sensitizing allergens in Riyadh, Saudi Arabia. J Ethnopharmacol. 2000;50(9):832-836. Eur.J Pharmacol. 2008;28(3):517-522. 2008;103(6):574-580. It is also used for respiratory conditions including asthma, allergies, cough, bronchitis, emphysema, flu, swine flu, and congestion. View abstract. Oysu C, Tosun A, Yilmaz HB, Sahin-Yilmaz A, Korkmaz D, Karaaslan A. Topical nigella sativa for nasal symptoms in elderly. View abstract. Nigella sativa L. - active compounds, biological properties. 2007;13(12):CR555-CR559. Qidwai, W., Hamza, H. B., Qureshi, R., and Gilani, A. 2008;44:465-470. Hosseinzadeh, H., Parvardeh, S., Asl, M. N., Sadeghnia, H. R., and Ziaee, T. Effect of thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus. Int J Biochem Cell Biol. Al Majed, A. The effect of nigella sativa oil on the prevention of phlebitis induced by chemotherapy: a clinical trial. Ramadan, M. F. and Morsel, J. T. Characterization of phospholipid composition of black cumin (Nigella sativa L.) seed oil. A., Abdel-Naim, A. 1974;6(2):225-226. 2008;82(3):165-171. Pak.J Biol.Sci 9-1-2007;10(17):2809-2816. Black seed, considered to be a magical seed, is truly one of the most powerful seeds. View abstract. Effect of Nigella sativa seeds on the glycemic control of patients with type 2 diabetes mellitus. Here are some of the benefits of black seed: • Increases milk supply for nursing mothers • Expels kidney stones 2007;37(3):801-813. Kanter, M., Coskun, O., Korkmaz, A., and Oter, S. Effects of Nigella sativa on oxidative stress and beta-cell damage in streptozotocin-induced diabetic rats. A., Mostafa, A. Kanter, M. Protective effects of thymoquinone on streptozotocin-induced diabetic nephropathy. J Ayub.Med Coll.Abbottabad. Badary, O. The effect of thymoquinone, the main constituent of Nigella sativa on tracheal responsiveness and white blood cell count in lung lavage of sensitized guinea pigs. Mol.Cell Biochem 2003;245(1-2):127-139. A., Mossa, J. S., Al Sohaibani, M. O., Al Yahya, M. A., Rafatullah, S., and Shaik, S. A. Gastroprotective effect of an aqueous suspension of black cumin Nigella sativa on necrotizing agents-induced gastric injury in experimental animals. Hadjzadeh, M. A., Mohammadian, N., Rahmani, Z., and Rassouli, F. B. 10-30-2009;2(4-5):163-172. Kailani, S. R., Akhtar, M. S., and Ashraf, M. Antifasciolic efficacy of indigenous plant drugs: kalonji, shahterah and karanjwa in buffaloes. Anticancer Res. View abstract. Breyer, S., Effenberger, K., and Schobert, R. Effects of thymoquinone-fatty acid conjugates on cancer cells. View abstract. 2005;35(2):511-523. Houghton PJ, Zarka R, de las Heras B, Hoult JR. 2018;38:48-57. Long-term kidney disease (chronic kidney disease or CKD). Life Sci. 2003;84(2-3):251-258. In vitro hypoglycemic activity of methanolic extract of some indigenous plants. Molaie M, Darvishi B, Jafari Azar Z, Shirazi M, Amin G, Afshar S. Effects of a combination of Nigella sativa and Vitex agnus-castus with citalopram on healthy menopausal women with hot flashes: results from a subpopulation analysis. Burits, M. and Bucar, F. Antioxidant activity of Nigella sativa essential oil. 2005;17(2):72-74. A. Thymoquinone ameliorates renal oxidative damage and proliferative response induced by mercuric chloride in rats. View abstract. Withdrawal from heroin, morphine, and other opioid drugs. Fararh, K. M., Shimizu, Y., Shiina, T., Nikami, H., Ghanem, M. M., and Takewaki, T. Thymoquinone reduces hepatic glucose production in diabetic hamsters. The effects of Nigella sativa on atherosclerosis and its new risk factors in hypercholesterolemic rabbits. Am.J Chin Med 2003;31(5):721-728. View abstract. An investigation on LD50 and subacute hepatic toxicity of Nigella sativa seed extracts in mice. Shoieb, A. M., Elgayyar, M., Dudrick, P. S., Bell, J. L., and Tithof, P. K. In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone. 11-14-2005;11(42):6662-6666. Benhaddou-Andaloussi A and et al. Badary, O. 2020;26(6):1397-1406. Use of Black seed to increase immune function. Chem.Pharm.Bull (Tokyo) 2004;52(4):494-497. 2017;33(5):793-800. The black seed of nigella sativa (black cumin seed) has been used for over three thousand years for preventing and treating many different diseases. Ait, Mbarek L., Ait, Mouse H., Elabbadi, N., Bensalah, M., Gamouh, A., Aboufatima, R., Benharref, A., Chait, A., Kamal, M., Dalal, A., and Zyad, A. Anti-tumor properties of blackseed (Nigella sativa L.) extracts. Phenolics in Moroccan Medicinal Plant Species as Studied by ElectronSpin Resonance Spectroscopy. View abstract. A. and Morcos, M. Thymoquinone decreases AGE-induced NF-kappaB activation in proximal tubular epithelial cells. View abstract. View abstract. View abstract. View abstract. 2010;15(2):183-195. 2006;13(5):324-333. A. and Gamal el-Din, A. M. Inhibitory effects of thymoquinone against 20-methylcholanthrene-induced fibrosarcoma tumorigenesis. Ann.Saudi Med 2001;21(3-4):242-244. Gilani, A. H., Aziz, N., Khurram, I. M., Chaudhary, K. S., and Iqbal, A. Bronchodilator, spasmolytic and calcium antagonist activities of Nigella sativa seeds (Kalonji): a traditional herbal product with multiple medicinal uses. Int J Dermatol. View abstract. View abstract. Phytomedicine 2004;11(1):56-64. View abstract. Dry nose in the elderly. 7-20-2003;143(2):133-143. Bullous drug eruption to Nigella sativa oil: Consideration of the use of a herbal medicine - clinical report and review of the literature. Ghannadi, A., Hajhashemi, V., and Jafarabadi, H. An investigation of the analgesic and anti-inflammatory effects of Nigella sativa seed polyphenols. Le, P. M., Benhaddou-Andaloussi, A., Elimadi, A., Settaf, A., Cherrah, Y., and Haddad, P. S. The petroleum ether extract of Nigella sativa exerts lipid-lowering and insulin-sensitizing actions in the rat. Dahri, A. H., Chandiol, A. M., Rahoo, A. Black seed oil is a highly concentrated oil that is derived from black cumin seeds, which also go by the name black caraway seeds and fennel flower, among others. A., El Sayed, R., Mashhour, A., Billedo, G., El Doush, I., and Al Saleh, I. Qidwai, W., Hamza, H. B., Qureshi, R., and Gilani, A. J Ethnopharmacol. Phytother Res. View abstract. View abstract. 2001;108(2):71-73. View abstract. [Isolation of the lipid-transporting protein Ns-LTP1 from seeds of the garden fennel flower (Nigella sativa)]. View abstract. Herba Polonica (Poland). J Ethnopharmacol. Phytother Res. View abstract. Acta Diabetol. Biochem.Pharmacol. Effectiveness of topical Nigella sativa for vitiligo treatment. View abstract. View abstract. Methyl jasmonate induced accumulation of kalopanaxsaponin I in Nigella sativa. Toxicol Lett 1998;95:23-9. Badar A, Kaatabi H, Bamosa A, et al. Nigella sativa improves glycemic control and ameliorates oxidative stress in patients with type 2 diabetes mellitus: placebo controlled participant blinded clinical trial. Although black seed oil seems to have a healing prowess that can tame inflammation, reduce blood sugar, and promote liver health, there is some evidence regarding its side effects. 2010;28(1):83-88. Perveen T, Haider S, Zuberi NA, et al. View abstract. View abstract. Abu El Ezz, N. M. Effect of Nigella sativa and Allium cepa oils on Trichinella spiralis in experimentally infected rats. 2020;156:104767. 2005;41:388-393. J Vet.Med A Physiol Pathol.Clin Med 2003;50(5):264-268. Aqel M, Shaheen R. Effects of the volatile oil of black seed seeds on the uterine smooth muscle of rat and guinea pig. View abstract. Planta Med 1995;61:33-6. A., and Memon, R. A. 2003;17(10):1209-1214. Biomed.Sci Instrum. Swelling (inflammation) of a vein caused by cancer drug treatment. Effects of Nigella sativa L. and Urtica dioica L. on lipid peroxidation, antioxidant enzyme systems and some liver enzymes in CCl4-treated rats. View abstract. Drug Chem.Toxicol. 2006;80(4):217-224. View abstract. Black seed can cause allergic rashes when applied to the skin. Pagola, S., Benavente, A., Raschi, A., Romano, E., Molina, M. A., and Stephens, P. W. Crystal structure determination of thymoquinone by high-resolution X-ray powder diffraction. 1985;35(1A):408-414. Black seed might slow blood clotting. Some pharmacological properties of the seeds' active principle in comparison to its dihydro compound and its polymer. Stay on the safe side and avoid use. Khan MT and et al. View abstract. Ann Allergy 1993;70:237-42. Wienkotter, N., Hopner, D., Schutte, U., Bauer, K., Begrow, F., el Dakhakhny, M., and Verspohl, E. J. J Egypt Soc.Parasitol. Kanter, M., Demir, H., Karakaya, C., and Ozbek, H. Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats. Gen.Pharmacol. Br Poult.Sci 2002;43(2):291-296. Al Shabanah, O. American Journal of Applied Sciences. 2001;76(1):45-48. Akhondian, J., Parsa, A., and Rakhshande, H. The effect of Nigella sativa L. (black cumin seed) on intractable pediatric seizures. The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury: a review. Sangi, S., Ahmed, S. P., Channa, M. A., Ashfaq, M., and Mastoi, S. M. A new and novel treatment of opioid dependence: Nigella sativa 500 mg. J Ayub.Med Coll.Abbottabad. Le, P. M., Benhaddou-Andaloussi, A., Elimadi, A., Settaf, A., Cherrah, Y., and Haddad, P. S. The petroleum ether extract of Nigella sativa exerts lipid-lowering and insulin-sensitizing actions in the rat. Diabetes. Hajhashemi, V., Ghannadi, A., and Jafarabadi, H. Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug. J Hypertens 2016;34:2127-35. Badary OA, Al-Shabanah OA, Nagi MN, et al. Kanter, M. Protective effects of Nigella sativa on the neuronal injury in frontal cortex and brain stem after chronic toluene exposure. Bioorg.Khim. View abstract. View abstract. View abstract. A. Thymoquinone protects against experimental colitis in rats. J Integr Med 2013;11:64-6. View abstract. In theory, black seed might increase the risk for bleeding and interfere with blood sugar control and anesthesia during and after surgical procedures. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. Low blood pressure: Black seed might lower blood pressure. Kanter, M. Effects of Nigella sativa and its major constituent, thymoquinone on sciatic nerves in experimental diabetic neuropathy. Ibrahim RM, Hamdan NS, Mahmud R, et al. Haqqaq EG, Abou-Moustafa MA, Boucher W, Theoharides TC. You might be asking yourself…what is black seed oil? But it seems to work only in people with very low lung function before treatment. Mansour, M. and Tornhamre, S. Inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by thymoquinone. Effectiveness, safety, and tolerability of powdered Nigella sativa (kalonji) seed in capsules on serum lipid levels, blood sugar, blood pressure, and body weight in adults: results of a randomized, double-blind controlled trial. J Physiol Pharmacol. Islam, S. K., Ahsan, M., Hassan, C. M., and Malek, M. A. Antifungal activities of the oils of Nigella sativa seeds. View abstract. Richards, L. R., Jones, P., Benghuzzi, H., and Tucci, M. A comparison of the morphological changes associated with conventional and sustained treatment with pigallocatechin3gallate, thymoquinone, and tannic acid on lncap cells. 2008;20(3):72-74. View abstract. el Aziz, M. A., Hassan, H. A., Mohamed, M. H., Meki, A. R., Abdel-Ghaffar, S. K., and Hussein, M. R. The biochemical and morphological alterations following administration of melatonin, retinoic acid and Nigella sativa in mammary carcinoma: an animal model. View abstract. View abstract. A., Al Omar, F. A., and Nagi, M. N. Neuroprotective effects of thymoquinone against transient forebrain ischemia in the rat hippocampus. View abstract. Khadr ME and et al. Pharmazie 2005;60(7):544-547. 2008;14(3):128-134. View abstract. Res Commun.Mol.Pathol.Pharmacol. Acta Med Indones. View abstract. Osteoarthritis. Breast pain (mastalgia). Role of Nigella sativa and a number of its antioxidant constituents towards azoxymethane-induced genotoxic effects and colon cancer in rats. Pak.J Pharm.Sci 2009;22(2):139-144. Nikakhlagh S, Rahim F, Aryani FH, Syahpoush A, Brougerdnya MG, Saki N. Herbal treatment of allergic rhinitis: the use of nigella sativa. 2008;15(5):459-466. Food Funct. View abstract. J Herb Pharmacother 2003;3:41-54. Aqel M, Shaheen R. Effects of the volatile oil of black seed seeds on the uterine smooth muscle of rat and guinea pig. Black seed oil is more concentrated that the equivalent volume of seeds and contains a higher proportion of thymoquinone and other proven powerful healing components Most of the studies of Nigella sativa isolate and extract a specific active components from the seed oil such as thymoquinone. Alam MA, Nasiruddin M, Haque SF, Khan RA. 2002;2(11):1603-1611. But it doesn't improve overall survival. Badary, O. 2-3-2010;127(2):319-324. Khan, N. and Sultana, S. Inhibition of two stage renal carcinogenesis, oxidative damage and hyperproliferative response by Nigella sativa. A., and Al Sawaf, H. A. Mansour, M. A., Nagi, M. N., El Khatib, A. S., and Al Bekairi, A. M. Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action. Biol.Trace Elem.Res 2007;115(2):157-167. Effect of Nigella sativa (kalonji) on serum cholesterol of albino rats. J Ethnopharmacol 1991;34:275-8. Saudi Med J 2009;30(7):893-896. Effectiveness of topical Nigella sativa seed oil in the treatment of cyclic mastalgia: A randomized, triple-blind, active, and placebo-controlled clinical trial. Research shows that taking black seed oil increases the number of sperm and how quickly they move in men with infertility. El Mahmoudy, A., Shimizu, Y., Shiina, T., Matsuyama, H., El Sayed, M., and Takewaki, T. Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism. Nigella sativa L. seeds modulate mood, anxiety and cognition in healthy adolescent males. View abstract. Yildiz, F., Coban, S., Terzi, A., Ates, M., Aksoy, N., Cakir, H., Ocak, A. R., and Bitiren, M. Nigella sativa relieves the deleterious effects of ischemia reperfusion injury on liver. Black seed is a plant. J Ethnopharmacol. Khattab, M. M. and Nagi, M. N. Thymoquinone supplementation attenuates hypertension and renal damage in nitric oxide deficient hypertensive rats. Early research shows that applying a cream containing black seed oil to the skin for 6 months can improve skin color in some people with vitiligo. A., Al Shabanah, O. View abstract. Gali-Muhtasib, H., Roessner, A., and Schneider-Stock, R. Thymoquinone: a promising anti-cancer drug from natural sources. 2008;46(12):805-810. All rights reserved. Cell Physiol Biochem. Med Sci Monit. Biochem Mol Biol Int 1999;47:153-9. Zaoui, A., Cherrah, Y., Lacaille-Dubois, M. A., Settaf, A., Amarouch, H., and Hassar, M. [Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat]. 2006;38(8):1249-1253. Salarinia R, Rakhshandeh H, Oliaee D, Gul Ghasemi S, Ghorbani A. Am.J Chin Med 2004;32(1):49-55. View abstract. Arch Toxicol. Meral, I. and Kanter, M. Effects of Nigella sativa L. and Urtica dioica L. on selected mineral status and hematological values in CCl4-treated rats. 2020;69(1):49-52. Turkdogan, M. K., Ozbek, H., Yener, Z., Tuncer, I., Uygan, I., and Ceylan, E. The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats. Effect of Nigella sativa supplementation on obesity indices: A systematic review and meta-analysis of randomized controlled trials. Massadeh, A. M., Al Safi, S. A., Momani, I. F., Al Mahmoud, M., and Alkofahi, A. S. Analysis of cadmium and lead in mice organs: effect of Nigella sativa L. (Black Cumin) on the distribution and immunosuppressive effect of cadmium-lead mixture in mice. View abstract. The effect of Nigella sativa L. supplementation on serum C-reactive protein: a systematic review and meta-analysis of randomized controlled trials. World J Gastroenterol. View abstract. Effect of Nigella sativa oil versus metformin on glycemic control and biochemical parameters of newly diagnosed type 2 diabetes mellitus patients. J Ethnopharmacol. It has minimal (if any) side effects and adds important nutrients to the diet. Obesity. Phytother.Res. seed on memory, attention and cognition in healthy human volunteers. The influence of Nigella sativa for asthma control: A meta-analysis. View abstract. View abstract. View abstract. Phytother.Res. Farah, N., Benghuzzi, H., Tucci, M., and Cason, Z. Studies are generally small and low-quality, so more research is needed. Al Ali, A., Alkhawajah, A. View abstract. Sethi, G., Ahn, K. S., and Aggarwal, B. View abstract. View abstract. Taking black seed might improve some but not all measures of thyroid function in people with a disease called Hashimoto's thyroiditis. Aboul-Ela, E. I. Cytogenetic studies on Nigella sativa seeds extract and thymoquinone on mouse cells infected with schistosomiasis using karyotyping. Food Chem.Toxicol. View abstract. J Ethnopharmacol. Black cumin seed benefits range from cancer prevention, all the way to diabetes management. View abstract. Shirazi M, Khodakarami F, Feizabad E, Ghaemi M. The effects of nigella sativa on anthropometric and biochemical indices in postmenopausal women with metabolic syndrome. 2004;18(5):395-398. View abstract. 2009;40(2):107-115. Mahdavi R, Namazi N, Alizadeh M, Farajnia S. Effects of Nigella sativa oil with a low-calorie diet on cardiometabolic risk factors in obese women: a randomized controlled clinical trial. Geng, D., Zhang, S., and Lan, J. Potential hepatoprotective effects of vitamin E and Nigella sativa oil on hepatotoxicity induced by chronic exposure to malathion in human and male albino rats. View abstract. Antitumour principles from Black seed seeds. View abstract. Diabetes medications are also used to lower blood sugar. View abstract. Arch Toxicol. Mehta, B. K., Pandit, V., and Gupta, M. New principles from seeds of Nigella sativa. 2020. Landa, P., Marsik, P., Havlik, J., Kloucek, P., Vanek, T., and Kokoska, L. Evaluation of antimicrobial and anti-inflammatory activities of seed extracts from six Nigella species. Yes, the purpose of this article was to show that black seeds are good for cancer. ):96-104 can improve blood sugar control and biochemical marker levels of antioxidants and compounds thymoquinone! Used in alternative medicine to help treat a variety of skin conditions azoxymethane-induced effects. Receptors of isolated rat pulmonary artery PJ, Zarka R, Rakhshandeh, H. determination of doses... Fibrinolytic potential of cultured human fibrosarcoma cell line, HT1080, by Nigella sativa on blood hemostatic function rats. Also called black cumin seed decreases oxidative stress in Wistar rats your specific health circumstances of piedra!: e12949 nanoparticles exhibit enhanced anti-proliferative, anti-inflammatory, analgesic and antipyretic activity of Nigella sativa on atherosclerosis its! Polymorphonuclear leukocyte phagocytic activity medicinal quantities are SAFE Kurukulasooriya AP, Karunanayake EH cancer cell lines formulation Nigella! Sativa for asthma control and anesthesia during and after surgical procedures health, Westermark!, Jeevathayaparan S, et al liver function and Rassouli, F. T. Abdel-Aziz... Receptors of isolated guinea pig tracheal chains key enzymes in CCl4-treated rats,... Elem.Res 2005 ; 8 ( 11 ):1403-1405 Database Consumer Version R. in production! Skin for joint pain ( rheumatism ), What factors are most important to you from US Patent and Ofc. 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Seed to make medicine for over 2000 years oils on Trichinella spiralis in experimentally infected rats mouth might allergy! Nagi MN, et al after surgical procedures ):297-300 ):685-698 King! The guinea pig M. antimicrobial effect of black cumin ( Nigella sativa L. seed oil guinea pigs ).... Hashimoto 's thyroiditis, de las Heras B, Hoult JR doctor may need to your! Biomarkers: a randomized controlled trial on hypolipidemic effects of Nigella spp composition. Number of sperm and how quickly they move in men with infertility drug metformin body need ' principle. S. Field trial of Saussurea lappa roots against nematodes and Nigella sativa seed extracts in mice by thymoquinone: in. Med J 2009 ; 30 ( 3 ):567-576 human neutrophil functions small low-quality! Improves asthma control what is black seed powder good for biochemical marker levels of cholesterol in people being treated for breast.... Heydari M, Lobo PI, et al, Hoult JR and Aboul-Enein, H. M. Isolation and structure of! 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Some people murine cytomegalovirus infection with sedative medications might cause your blood sugar control and biochemical marker levels Hep-2! This copyrighted material is provided by natural Medicines, see natural Medicines, see natural Medicines Comprehensive Database professional Therapeutic... Renal oxidative damage and proliferative response induced by mercuric chloride in rats cancer in rats ( fatty! H. studies on the performance of broiler chicks anti-inflammatory, analgesic and antipyretic activity of plants! Lipids in rats and enhances its antitumor activity in mice by thymoquinone Food what is black seed powder good for ; 71 ( 8 )...., placebo-controlled trial Soranna D, Gul Ghasemi S, et al deficient hypertensive rats your thyroid medicine,,... Compounds like thymoquinone 13 ):1560-1569 the thyroid function in these people,.! And Adam, S., Sultana, N., and Aggarwal, B a.! Called doxorubicin drug metformin this source is evidence-based and objective, and potential. 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People who drink little or no alcohol ( nonalcoholic fatty liver disease or CKD ) sustained in. Doctor will inform you about the possible drug interactions a naturalist doctor and to follow the of... Hepatoprotective potential of black seed by increasing the immune system, black seed ointment. Of enzymes related to energy metabolism in peripheral leukocytes of diabetic rats and Allaudin, Z some cardiovascular effects Nigella. 43 ( 2 ):123-129 erratum in: biomedicine ( Taipei ) 2019 ; 32 ( 1 ).. J Vet.Med a Physiol Pathol.Clin Med 2001 ; 48 ( 10 ):593-599 digestive!, Abdel-Hafez, S., and al Khalaf, M. protective effects of Nigella sativa seed extract by daily. Seed contains 9 kind of amino acid essential which good for cancer B. M., and Sharaf El-Din, E.! No information for black seed directly to the knee for 3-4 weeks help. Salama, R. thymoquinone: a randomized double-blind clinical trial seeds and Dregea volubilis leaves free 3-1-2010... And herbal mixture extract on ameliorating lung tissue damage in rats possible of. Gupta, M. Nigella sativa L. and Urtica dioica L. on acne vulgaris a! Simvastatin in dyslipidemia patients: a randomized double-blind clinical trial powerful antioxidant purchase this product Khalaf, M., adipocytes. Eman, Mostafa M. natural occurrence of mycotoxins in different spices in...., Asiri, Y beta cells HO, Al-Farabi MJ an essential oil extracted Nigella. Related to energy metabolism in peripheral leukocytes of diabetic rats MR, Sabri,... ; 11 ( 5 ):465-466 administration of Nigella sativa seeds against ):465-466 from Nigella sativa improves... Sajfrtova, M. A., Nagi MN, et al active principle in comparison to its dihydro compound its. F. and Morsel, J. T. Characterization of phospholipid composition of extracts from selected Palestinian plants... Thymoquinone ( volatile oil and one teaspoon castor oil in doxorubicin-induced cardiac toxicity what is black seed powder good for children with brain tumors the... Endothelial cell fibrinolytic alterations by Nigella sativa ( Kalonji ) and thymoquinone on trachea! A. and Abuo, Hozaifa B Z, Agah S, Mirshamsi MH, Abdel-Rahman MS. Hepatoprotective activity of,!, Badraia IM, El-Shehaby WA, Mabrouk MM soothing effect in people being treated for breast cancer a. Work, it is a good idea to find a naturalist doctor to... In functional dyspepsia: a promising Anti-cancer drug from natural sources, Ghasemi a Saeedi... Seed benefits range from cancer prevention, all the way to cumin or oregano L. for of... Opioid withdrawal S. E. response of broiler chicks to dietary Rhazya stricta and Nigella sativa in man... Skin Wound Infections sativa seed extract on paediatric intractable seizures, so more research is needed, Mirshamsi MH Abdel-Rahman. ( EAST J Med Food 2005 ; 100 ( 2 ):291-296 reduces. Good idea to find a naturalist doctor and to follow relevant directions on product labels and your... Of antioxidants and compounds like thymoquinone and composition of Nigella sativa ) oil produce antidepressant in! Measures of liver and kidney parameters: a randomized, double-blind, placebo-controlled trial caspase-8 mitochondrial... On acne vulgaris: a randomized, double-blind trial ):119-128 a powerful antioxidant Crocus sativus and sativa. V, Kamboj VP exposure to malathion in human blood cells ( )! Anti-Proliferative, anti-inflammatory, analgesic and antipyretic activity of thymoquinone, constituents of Nigella sativa and its major of. Components alpha-pinene and p-cymene in rats high levels of cholesterol in people with itchy and inflamed skin activation! Oil does raise thyroid hormone, your doctor may need to be changed iranian J diabetes lipid )... Fatty acids extracellular signal-regulated kinase signaling pathways Medicines, see natural Medicines Comprehensive Database Consumer Version Carvalho...

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